AMPK, Sirtuins, mTOR: Pathways to Longevity

AMPK, Sirtuins, mTOR: Pathways to Longevity

Longevity research has identified three important signaling pathways in the body that slow down the ageing process and promote health. They act as energy and nutrient sensors in the body and react to changes in our cells. Each pathway has its own mechanism that...
Exercise, Heat, Cold & Other Adversity Mimetics for Longevity

Why Do We Age?

In this podcast episode, Dr. David Sinclair and co-host Matthew LaPlante discuss why we age. In doing so, they discuss organisms that have extreme longevity, the genes that control aging (i.e. mTOR, AMPK, Sirtuins), the role of sirtuin proteins as epigenetic...
Why We Age, And Why We Don’t Have To

Why We Age, And Why We Don’t Have To

An interview by neuroscientist Andrew Huberman with David Sinclair, Professor of Genetics at Harvard Medical School and an expert researcher in the field of longevity. In this podcast episode, Andrew Huberman and David Sinclair discuss the cellular and molecular...