In this episode, Harvard professor Dr. David Sinclair and co-host Matthew LaPlante discuss how frequently we should eat, what food we should avoid, and what food we should pursue. They discuss the science behind how a “low energy state,” which can be induced by a period of fasting, combats aging and promotes health. They also walk through research that points to the benefits of a mostly plant-based diet for slowing aging and offer key insights into when to eat and what to eat to maximize longevity.
Links:
Dietary restriction extends lifespan in dogs – https://bit.ly/3FlDo4y 
Intermittent fasting in patients with metabolic syndrome – https://go.nature.com/3FggKKZ 
Alternate day fasting in healthy, non-obese humans – https://bit.ly/3HXGptH 
Time-restricted feeding in humans with prediabetes – https://bit.ly/3ffZWct 
A 24-hour fast reduces inflammasome activation in humans – https://bit.ly/3fwDc8t 
Fasting and diabetes – https://bit.ly/3rdtRHQ 
Intermittent energy restriction and multiple sclerosis – https://bit.ly/3HV7i1o 
A fasting-mimicking diet in patients with breast cancer – https://go.nature.com/3flcbV2 
Mouse genetics influence how diet affects lifespan – https://bit.ly/3qiBc9R 
Vegetarian dietary patterns and human mortality – https://bit.ly/31OCtMq 
A Mediterranean diet slows biological aging – https://bit.ly/3I1rcbd 
Plant polyphenols regulate lifespan in yeast – https://go.nature.com/3HWWGiB 
A Mediterranean diet is linked to reduced mortality – https://bit.ly/3fdDPDx
 
				


